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71142-71-7

D-Phenylalanyl-prolyl-arginyl chloromethyl ketone

Catalog#: AR01EALW  |   CAS#: 71142-71-7  |   MDL#:  |   MF: C21H31ClN6O3  |   MW: 450.9622

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Catalog Number AR01EALW
Chemical Name D-Phenylalanyl-prolyl-arginyl chloromethyl ketone
CAS Number 71142-71-7
Molecular Formula C21H31ClN6O3
Molecular Weight 450.9622
SMILES ClCC(=O)C(N1CCCC1C(=O)NC(=O)C(Cc1ccccc1)N)CCCN=C(N)N 

The application of PPACK (phenylmethylsulfonyl fluoride) in chemical synthesis is vital for inhibiting serine proteases, specifically thrombin. PPACK irreversibly binds to the active site of thrombin, effectively blocking its catalytic activity. This allows researchers to study the role of thrombin in various biological processes and develop potential therapeutic strategies. Additionally, PPACK is commonly utilized in biochemical assays to assess the activity of serine proteases and investigate their mechanisms of action. Its precise mechanism of inhibition and high specificity make PPACK a valuable tool in the field of chemical synthesis and protease research.
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