
Catalog Number	AR008RZ9
Chemical Name	Daptomycin
CAS Number	103060-53-3
Molecular Formula	C72H101N17O26
Molecular Weight	1620.6706399999994
MDL Number	MFCD08282794
SMILES	NCCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3c2cccc3)NC(=O)CCCCCCCCC)CC(=O)N)CC(=O)O)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CC(=O)O)C)CC(=O)O)CO)[C@@H](CC(=O)O)C)CC(=O)c1ccccc1N

  1.Natural products to drugs: daptomycin and related lipopeptide antibiotics. Richard H. Baltz, Vivian Miao, Stephen K. Wrigley , Nat. Prod. Rep. , 2005 , 22 , 717

  2.Structural diversity, biosynthesis, and biological functions of lipopeptides from Streptomyces. Songya Zhang, Yunliang Chen, Jing Zhu, Qiujie Lu, Max J. Cryle, Youming Zhang, Fu Yan , Nat. Prod. Rep. , 2023 , 40 , 557

  3.The impact of lysyl-phosphatidylglycerol on the interaction of daptomycin with model membranes. Ryan Moreira, Scott D. Taylor , Org. Biomol. Chem. , 2022 , 20 , 9319

  4.Rhombohedral trap for studying molecular oligomerization in membranes: application to daptomycin. Ming-Tao Lee, Wei-Chin Hung, Huey W. Huang , Soft Matter , 2019 , 15 , 4326

  5.Daptomycin and AgNP co-loaded rGO nanocomposites for specific treatment of Gram-positive bacterial infection in vitro and in vivo. Chunyi Tong, Li Li, Feng Xiao, Jialong Fan, Xianghua Zhong, Xuanming Liu, Bin Liu, Zhaohui Wu, Jianqun Zhou , Biomater. Sci. , 2019 , 7 , 5097

  6.A combined solid- and solution-phase approach provides convenient access to analogues of the calcium-dependent lipopeptide antibiotics. Peter 't Hart, Laurens H. J. Kleijn, Gerjan de Bruin, Sabine F. Oppedijk, Johan Kemmink, Nathaniel I. Martin , Org. Biomol. Chem. , 2014 , 12 , 913

  7.NMR structure determination and calcium binding effects of lipopeptide antibiotic daptomycin. Lee-Jon Ball, Catherine M. Goult, James A. Donarski, Jason Micklefield, Vasudevan Ramesh , Org. Biomol. Chem. , 2004 , 2 , 1872

  8.The calcium-dependent lipopeptide antibiotics: structure, mechanism, & medicinal chemistry. Thomas M. Wood, Nathaniel I. Martin , Med. Chem. Commun. , 2019 , 10 , 634

  9.Natural products acting against S. aureus through membrane and cell wall disruption. Gautam Kumar, Kritika Engle , Nat. Prod. Rep. , 2023 , 40 , 1608

  10.Recent applications of solid-phase strategy in total synthesis of antibiotics. Yuxin Zhou, Xiao-Wei Liang , RSC Adv. , 2021 , 11 , 37942

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GHS Pictogram
Signal Word	Warning
UN#	-
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305+P351+P338
Class	-
Packing Group	-

Packsize	Purity	Price	Availability
10mg	98%	$17.00	Global Stock	Buy Now	Add To Cart
50mg	98%	$60.00	Global Stock	Buy Now	Add To Cart
100mg	98%	$61.00	Global Stock	Buy Now	Add To Cart
250mg	98%	$90.00	Global Stock	Buy Now	Add To Cart
1g	98%	$226.00	Global Stock	Buy Now	Add To Cart